In this video, we use OncoLand to find a list of the highest frequency mutations per tumor type across TCGA, limited to a list of known tumor suppressors. This technique can easily be extended for any gene, and the categorization can be across all tumor types, histologies, or any other classification available in the system or that you create. It also applies to all datasets, not just TCGA, so could easily be applied to ICGC, CCLE, etc.
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Keeping you up-to-date with the latest in NGS, Bioinformatics Analysis, and cancer genomics with blogs on Array Suite, OncoLand (TCGA and more), ImmunoLand, and more.