Fusion genes are genes that made by joining parts of two different genes, caused by chromosome translocations, inversions and deletions. Fusion genes can play an important role in cancer mutations that have multiple effects on a target gene. At Omicsoft, we provide a powerful fusion detection algorithm in FusionMap. Recently, we implemented a new Fusion Genome Browser view in our "Lands", like OncoLand, to provide dynamic fusion visualization.
The example genome browser above clearly shows the 3 prime end of FGFR3 has less coverage in fusion positive samples in comparison with those in fusion negative samples, due to the fusion with TACC3.
The Fusion Genome Browser view is interactive and filterable, by fusion information or by sample Meta Data and Clinical Data, along with other hundreds of annotations: